ctcRbase

Entry Detail

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General Information

Database ID: PRAD08498 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: OTULIN Full Name: OTU deubiquitinase with linear linkage specificity Category: mRNA Synonyms: AIPDS|FAM105B|GUM Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 14664664 End Site(bp): 14699711 Gene Summary: This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000154124 HGNC ID: HGNC:25118 Entrez Gene: 90268

Expression Profile of OTULIN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES YES hsa-miR-132-3p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-194-5p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-370-3p YES YES NO hsa-miR-377-3p YES NO YES hsa-miR-429 YES YES NO hsa-miR-496 YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-590-5p YES YES NO Display: