| ncRNA Symbol: | IL17RA |
| Full Name: | interleukin 17 receptor A |
| Category: | mRNA |
| Synonyms: | CANDF5|CD217|CDw217|IL-17RA|IL17R|IMD51|hIL-17R |
| Chromosome: | chr22 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 17084954 | End Site(bp): | 17115694 |
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| Gene Summary: | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
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