ctcRbase

Entry Detail

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General Information

Database ID: PRAD08897 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: P3H2 Full Name: prolyl 3-hydroxylase 2 Category: mRNA Synonyms: LEPREL1|MCVD|MLAT4 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 189956728 End Site(bp): 190122437 Gene Summary: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] External Links: Ensembl ID: ENSG00000090530 HGNC ID: HGNC:19317 Entrez Gene: 55214

Expression Profile of P3H2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-197-3p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-204-5p NO YES YES hsa-miR-211-5p NO YES YES hsa-miR-21-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-760 YES NO YES Display: