| ncRNA Symbol: | APELA |
| Full Name: | apelin receptor early endogenous ligand |
| Category: | mRNA |
| Synonyms: | ELA|Ende|tdl |
| Chromosome: | chr4 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 164877004 | End Site(bp): | 164898965 |
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| Gene Summary: | This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016] |
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