| ncRNA Symbol: | IRF8 |
| Full Name: | interferon regulatory factor 8 |
| Category: | mRNA |
| Synonyms: | H-ICSBP|ICSBP|ICSBP1|IMD32A|IMD32B|IRF-8 |
| Chromosome: | chr16 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 85898803 | End Site(bp): | 85922609 | |
| Gene Summary: | Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008] |
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