ctcRbase

Entry Detail

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General Information

Database ID: PRAD09017 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SASH1 Full Name: SAM and SH3 domain containing 1 Category: mRNA Synonyms: SH3D6A|dJ323M4.1 Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 148272304 End Site(bp): 148552050 Gene Summary: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016] External Links: Ensembl ID: ENSG00000111961 HGNC ID: HGNC:19182 Entrez Gene: 23328

Expression Profile of SASH1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-128-3p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-144-3p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-21-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-376c-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-409-3p YES NO YES hsa-miR-410-3p YES YES YES hsa-miR-421 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-590-5p YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES YES Display: