ctcRbase

Entry Detail

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General Information

Database ID: PRAD09031 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PTPN22 Full Name: protein tyrosine phosphatase, non-receptor type 22 Category: mRNA Synonyms: LYP|LYP1|LYP2|PEP|PTPN22.5|PTPN22.6|PTPN8 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 113813811 End Site(bp): 113871759 Gene Summary: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000134242 HGNC ID: HGNC:9652 Entrez Gene: 26191

Expression Profile of PTPN22 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-155-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: