ctcRbase

Entry Detail

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General Information

Database ID: PRAD09351 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: FHL3 Full Name: four and a half LIM domains 3 Category: mRNA Synonyms: SLIM2 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 37996770 End Site(bp): 38005606 Gene Summary: The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000183386 HGNC ID: HGNC:3704 Entrez Gene: 2275

Expression Profile of FHL3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-137 YES NO YES hsa-miR-212-3p YES YES NO hsa-miR-25-3p YES NO YES hsa-miR-32-5p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES NO YES hsa-miR-367-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-92a-3p YES NO YES hsa-miR-92b-3p YES NO YES Display: