ctcRbase

Entry Detail

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General Information

Database ID: PRAD09529 Cancer Type: prostate cancer Dataset: GSE104209 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: OAS2 Full Name: 2'-5'-oligoadenylate synthetase 2 Category: mRNA Synonyms: - Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 112978395 End Site(bp): 113011723 Gene Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000111335 HGNC ID: HGNC:8087 Entrez Gene: 4939

Expression Profile of OAS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO hsa-miR-708-5p YES YES NO Display: