| ncRNA Symbol: | HLA-DOA | | Full Name: | major histocompatibility complex, class II, DO alpha | | Category: | mRNA | | Synonyms: | HLA-DNA|HLA-DZA|HLADZ | | Chromosome: | chr6 | | Strand: | - | | Coordinate: | | Start Site(bp): | 33004178 | End Site(bp): | 33009612 |
| | Gene Summary: | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] | | External Links: | |
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