ctcRbase

Entry Detail

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General Information

Database ID: PRAD10511 Cancer Type: prostate cancer Dataset: GSE67980 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: BPGM Full Name: bisphosphoglycerate mutase Category: mRNA Synonyms: DPGM Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 134646808 End Site(bp): 134679813 Gene Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000172331 HGNC ID: HGNC:1093 Entrez Gene: 669

Expression Profile of BPGM Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES NO Display: