| ncRNA Symbol: | FOSB | | Full Name: | FosB proto-oncogene, AP-1 transcription factor subunit | | Category: | mRNA | | Synonyms: | AP-1|G0S3|GOS3|GOSB | | Chromosome: | chr19 | | Strand: | + | | Coordinate: | | Start Site(bp): | 45467995 | End Site(bp): | 45475179 | | | Gene Summary: | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | | External Links: | |
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