ctcRbase

Entry Detail

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General Information

Database ID: PRAD11192 Cancer Type: prostate cancer Dataset: GSE67980 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SDC1 Full Name: syndecan 1 Category: mRNA Synonyms: CD138|SDC|SYND1|syndecan Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 20200797 End Site(bp): 20225433 Gene Summary: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000115884 HGNC ID: HGNC:10658 Entrez Gene: 6382

Expression Profile of SDC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-124-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-665 YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES NO YES Display: