Entry Detail



General Information

Database ID:PRAD11522
Cancer Type:prostate cancer
Dataset:GSE67980
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:HPGD
Full Name:15-hydroxyprostaglandin dehydrogenase
Category:mRNA
Synonyms:15-PGDH|PGDH|PGDH1|PHOAR1|SDR36C1
Chromosome:chr4
Strand:-
Coordinate:
Start Site(bp):174490177End Site(bp):174523154
Gene Summary:This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
External Links:
Ensembl ID:ENSG00000164120
HGNC ID:HGNC:5154
Entrez Gene:3248



Expression Profile of HPGD Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-194-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-29a-3p
NO
YES
YES
hsa-miR-29b-3p
NO
YES
YES
hsa-miR-29c-3p
NO
YES
YES
hsa-miR-31-5p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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