ctcRbase

Entry Detail

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General Information

Database ID: PRAD11680 Cancer Type: prostate cancer Dataset: GSE67980 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CHD3 Full Name: chromodomain helicase DNA binding protein 3 Category: mRNA Synonyms: Mi-2a|Mi2-ALPHA|ZFH Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 7884806 End Site(bp): 7912760 Gene Summary: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000170004 HGNC ID: HGNC:1918 Entrez Gene: 1107

Expression Profile of CHD3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-491-5p YES YES NO Display: