ctcRbase

Entry Detail

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General Information

Database ID: SKCM00220 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VIM Full Name: vimentin Category: mRNA Synonyms: - Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 17228259 End Site(bp): 17237593 Gene Summary: This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000026025 HGNC ID: HGNC:12692 Entrez Gene: 7431

Expression Profile of VIM Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-137 YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-876-5p YES YES NO Display: