ctcRbase

Entry Detail

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General Information

Database ID: SKCM00458 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HMGB2 Full Name: high mobility group box 2 Category: mRNA Synonyms: HMG2 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 173331695 End Site(bp): 173335125 Gene Summary: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000164104 HGNC ID: HGNC:5000 Entrez Gene: 3148

Expression Profile of HMGB2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-361-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-384 YES YES NO hsa-miR-421 YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-582-5p YES NO YES Display: