ctcRbase

Entry Detail

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General Information

Database ID: SKCM00517 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UBE2C Full Name: ubiquitin conjugating enzyme E2 C Category: mRNA Synonyms: UBCH10|dJ447F3.2 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 45812576 End Site(bp): 45816957 Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000175063 HGNC ID: HGNC:15937 Entrez Gene: 11065

Expression Profile of UBE2C Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO Display: