ctcRbase

Entry Detail

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General Information

Database ID: SKCM00566 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BIRC5 Full Name: baculoviral IAP repeat containing 5 Category: mRNA Synonyms: API4|EPR-1 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 78214186 End Site(bp): 78225636 Gene Summary: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011] External Links: Ensembl ID: ENSG00000089685 HGNC ID: HGNC:593 Entrez Gene: 332

Expression Profile of BIRC5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-873-5p YES YES NO Display: