Entry Detail



General Information

Database ID:SKCM00722
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MAGEB2
Full Name:MAGE family member B2
Category:mRNA
Synonyms:CT3.2|DAM6|MAGE-XP-2
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):30215560End Site(bp):30220089
Gene Summary:This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000099399
HGNC ID:HGNC:6809
Entrez Gene:4113



Expression Profile of MAGEB2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-142-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-34a-5p
YES
YES
NO
hsa-miR-34c-5p
YES
YES
NO
hsa-miR-449a
YES
YES
NO
hsa-miR-449b-5p
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
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