ctcRbase

Entry Detail

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General Information

Database ID: SKCM00770 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AKR1B1 Full Name: aldo-keto reductase family 1 member B Category: mRNA Synonyms: ADR|ALDR1|ALR2|AR Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 134442350 End Site(bp): 134459284 Gene Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009] External Links: Ensembl ID: ENSG00000085662 HGNC ID: HGNC:381 Entrez Gene: 231

Expression Profile of AKR1B1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-145-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-451a YES YES NO hsa-miR-488-3p YES YES YES Display: