ctcRbase

Entry Detail

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General Information

Database ID: SKCM00830 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LSM1 Full Name: LSM1 homolog, mRNA degradation associated Category: mRNA Synonyms: CASM|YJL124C Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 38163321 End Site(bp): 38176730 Gene Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000175324 HGNC ID: HGNC:20472 Entrez Gene: 27257

Expression Profile of LSM1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO Display: