| ncRNA Symbol: | LAMTOR3 |
| Full Name: | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| Category: | mRNA |
| Synonyms: | MAP2K1IP1|MAPBP|MAPKSP1|MP1|PRO0633|Ragulator3 |
| Chromosome: | chr4 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 99878336 | End Site(bp): | 99894490 |
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| Gene Summary: | This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] |
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