ctcRbase

Entry Detail

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General Information

Database ID: SKCM00903 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CRYZ Full Name: crystallin zeta Category: mRNA Synonyms: - Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 74705482 End Site(bp): 74733408 Gene Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000116791 HGNC ID: HGNC:2419 Entrez Gene: 1429

Expression Profile of CRYZ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-758-3p YES YES NO hsa-miR-96-5p YES YES NO Display: