ctcRbase

Entry Detail

---



General Information

Database ID: SKCM00905 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ORC5 Full Name: origin recognition complex subunit 5 Category: mRNA Synonyms: ORC5L|ORC5P|ORC5T|PPP1R117 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 104126341 End Site(bp): 104208047 Gene Summary: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000164815 HGNC ID: HGNC:8491 Entrez Gene: 5001

Expression Profile of ORC5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-218-5p NO YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES NO Display: