Entry Detail



General Information

Database ID:SKCM00914
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:BOLA3
Full Name:bolA family member 3
Category:mRNA
Synonyms:MMDS2
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):74135398End Site(bp):74147994
Gene Summary:This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046). [provided by RefSeq, Dec 2011]
External Links:
Ensembl ID:ENSG00000163170
HGNC ID:HGNC:24415
Entrez Gene:388962



Expression Profile of BOLA3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
YES
hsa-miR-107
YES
YES
YES
hsa-miR-129-5p
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
YES
hsa-miR-223-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
YES
hsa-miR-374b-5p
YES
YES
YES
hsa-miR-410-3p
YES
YES
NO
hsa-miR-424-5p
YES
YES
YES
hsa-miR-497-5p
YES
YES
YES
hsa-miR-7-5p
YES
YES
NO
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