Entry Detail



General Information

Database ID:SKCM00959
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ACAT1
Full Name:acetyl-CoA acetyltransferase 1
Category:mRNA
Synonyms:ACAT|MAT|T2|THIL
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):108121516End Site(bp):108147776
Gene Summary:This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009]
External Links:
Ensembl ID:ENSG00000075239
HGNC ID:HGNC:93
Entrez Gene:38



Expression Profile of ACAT1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-214-3p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-590-5p
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
Display: