Entry Detail


General Information

Database ID:SKCM01027
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PLK1
Full Name:polo like kinase 1
Category:mRNA
Synonyms:PLK|STPK13
Chromosome:chr16
Strand:+
Coordinate:
Start Site(bp):23677656End Site(bp):23690367
Gene Summary:The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]
External Links:
Ensembl ID:ENSG00000166851
HGNC ID:HGNC:9077
Entrez Gene:5347



Expression Profile of PLK1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-455-5p
YES
YES
NO
Display: