ctcRbase

Entry Detail

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General Information

Database ID: SKCM01059 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TARBP2 Full Name: TARBP2, RISC loading complex RNA binding subunit Category: mRNA Synonyms: LOQS|TRBP|TRBP1|TRBP2 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 53500921 End Site(bp): 53506431 Gene Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000139546 HGNC ID: HGNC:11569 Entrez Gene: 6895

Expression Profile of TARBP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-184 YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-98-5p YES YES YES Display: