Entry Detail



General Information

Database ID:SKCM01104
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SPTSSA
Full Name:serine palmitoyltransferase small subunit A
Category:mRNA
Synonyms:C14orf147|SSSPTA
Chromosome:chr14
Strand:-
Coordinate:
Start Site(bp):34432789End Site(bp):34462356
Gene Summary:Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
External Links:
Ensembl ID:ENSG00000165389
HGNC ID:HGNC:20361
Entrez Gene:171546



Expression Profile of SPTSSA Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
NO
hsa-miR-129-5p
YES
YES
YES
hsa-miR-132-3p
YES
YES
YES
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-155-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
YES
hsa-miR-18a-5p
YES
YES
NO
hsa-miR-18b-5p
YES
YES
NO
hsa-miR-196a-5p
YES
YES
YES
hsa-miR-196b-5p
YES
YES
YES
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-212-3p
YES
YES
YES
hsa-miR-221-3p
YES
YES
YES
hsa-miR-222-3p
YES
YES
YES
hsa-miR-300
YES
YES
YES
hsa-miR-320a
YES
YES
YES
hsa-miR-320b
YES
YES
YES
hsa-miR-320c
YES
YES
YES
hsa-miR-320d
YES
YES
YES
hsa-miR-323a-3p
YES
NO
YES
hsa-miR-335-5p
YES
YES
YES
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
YES
hsa-miR-411-5p
YES
YES
NO
hsa-miR-429
YES
YES
YES
hsa-miR-433-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
YES
hsa-miR-489-3p
YES
NO
YES
hsa-miR-494-3p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
hsa-miR-9-5p
YES
YES
YES
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