ctcRbase

Entry Detail

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General Information

Database ID: SKCM01161 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AURKA Full Name: aurora kinase A Category: mRNA Synonyms: AIK|ARK1|AURA|BTAK|PPP1R47|STK15|STK6|STK7 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 56369389 End Site(bp): 56392337 Gene Summary: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000087586 HGNC ID: HGNC:11393 Entrez Gene: 6790

Expression Profile of AURKA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-370-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-98-5p YES YES NO Display: