Entry Detail



General Information

Database ID:SKCM01350
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NEK2
Full Name:NIMA related kinase 2
Category:mRNA
Synonyms:HsPK21|NEK2A|NLK1|PPP1R111|RP67
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):211658657End Site(bp):211675630
Gene Summary:This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]
External Links:
Ensembl ID:ENSG00000117650
HGNC ID:HGNC:7745
Entrez Gene:4751



Expression Profile of NEK2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
YES
hsa-miR-150-5p
YES
YES
NO
hsa-miR-186-5p
NO
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-486-5p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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