ctcRbase

Entry Detail

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General Information

Database ID: SKCM01356 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BUB1 Full Name: BUB1 mitotic checkpoint serine/threonine kinase Category: mRNA Synonyms: BUB1A|BUB1L|hBUB1 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 110637698 End Site(bp): 110678114 Gene Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] External Links: Ensembl ID: ENSG00000169679 HGNC ID: HGNC:1148 Entrez Gene: 699

Expression Profile of BUB1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES YES NO Display: