ctcRbase

Entry Detail

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General Information

Database ID: SKCM01406 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BABAM2 Full Name: BRISC and BRCA1 A complex member 2 Category: mRNA Synonyms: BRCC4|BRCC45|BRE Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 27889941 End Site(bp): 28338901 Gene Summary: This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016] External Links: Ensembl ID: ENSG00000158019 HGNC ID: HGNC:1106 Entrez Gene: 9577

Expression Profile of BABAM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-182-5p YES YES YES hsa-miR-19b-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-384 YES YES YES hsa-miR-665 YES NO YES hsa-miR-758-3p YES YES NO Display: