Entry Detail



General Information

Database ID:SKCM01416
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GGPS1
Full Name:geranylgeranyl diphosphate synthase 1
Category:mRNA
Synonyms:GGPPS|GGPPS1
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):235327350End Site(bp):235344532
Gene Summary:This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
External Links:
Ensembl ID:ENSG00000152904
HGNC ID:HGNC:4249
Entrez Gene:9453



Expression Profile of GGPS1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-379-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-9-5p
YES
YES
NO
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