Entry Detail



General Information

Database ID:SKCM01592
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ABCE1
Full Name:ATP binding cassette subfamily E member 1
Category:mRNA
Synonyms:ABC38|OABP|RLI|RLI1|RNASEL1|RNASELI|RNS4I
Chromosome:chr4
Strand:+
Coordinate:
Start Site(bp):145097932End Site(bp):145129179
Gene Summary:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000164163
HGNC ID:HGNC:69
Entrez Gene:6059



Expression Profile of ABCE1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-1297
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
YES
hsa-miR-135b-5p
YES
YES
YES
hsa-miR-140-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
YES
hsa-miR-145-5p
YES
YES
NO
hsa-miR-153-3p
YES
YES
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
YES
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-299-3p
YES
YES
YES
hsa-miR-29a-3p
YES
YES
YES
hsa-miR-29b-3p
YES
YES
YES
hsa-miR-29c-3p
YES
YES
YES
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-369-3p
YES
NO
YES
hsa-miR-374a-5p
YES
YES
YES
hsa-miR-374b-5p
YES
YES
YES
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
YES
hsa-miR-655-3p
YES
NO
YES
hsa-miR-873-5p
YES
YES
NO
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