ctcRbase

Entry Detail

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General Information

Database ID: SKCM01600 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TIMM8A Full Name: translocase of inner mitochondrial membrane 8A Category: mRNA Synonyms: DDP|DDP1|DFN1|MTS|TIM8 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 101345661 End Site(bp): 101349196 Gene Summary: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000126953 HGNC ID: HGNC:11817 Entrez Gene: 1678

Expression Profile of TIMM8A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES NO YES hsa-miR-299-3p YES NO YES hsa-miR-300 YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-421 YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES Display: