ctcRbase

Entry Detail

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General Information

Database ID: SKCM01898 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NMT1 Full Name: N-myristoyltransferase 1 Category: mRNA Synonyms: NMT Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 45051610 End Site(bp): 45109016 Gene Summary: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008] External Links: Ensembl ID: ENSG00000136448 HGNC ID: HGNC:7857 Entrez Gene: 4836

Expression Profile of NMT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-100-5p YES YES NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-136-5p YES YES NO hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-182-5p YES YES YES hsa-miR-204-5p YES NO YES hsa-miR-211-5p YES NO YES hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-424-5p YES NO NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-9-5p YES YES YES hsa-miR-99a-5p YES YES NO hsa-miR-99b-5p YES YES NO Display: