ncRNA Symbol: | DLEU2 |
Full Name: | deleted in lymphocytic leukemia 2 |
Category: | lncRNA |
Synonyms: | ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS |
Chromosome: | chr13 |
Strand: | - |
Coordinate: | Start Site(bp): | 49982552 | End Site(bp): | 50125720 | |
Gene Summary: | This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] |
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