ctcRbase

Entry Detail

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General Information

Database ID: SKCM02665 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: COTL1 Full Name: coactosin like F-actin binding protein 1 Category: mRNA Synonyms: CLP Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 84565594 End Site(bp): 84618077 Gene Summary: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000103187 HGNC ID: HGNC:18304 Entrez Gene: 23406

Expression Profile of COTL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-1323 YES NO NO hsa-miR-138-5p YES NO YES hsa-miR-182-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-495-3p YES NO NO hsa-miR-548o-3p YES NO NO Display: