ctcRbase

Entry Detail

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General Information

Database ID: SKCM02975 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ATP1B1 Full Name: ATPase Na+/K+ transporting subunit beta 1 Category: mRNA Synonyms: ATP1B Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 169105697 End Site(bp): 169132722 Gene Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010] External Links: Ensembl ID: ENSG00000143153 HGNC ID: HGNC:804 Entrez Gene: 481

Expression Profile of ATP1B1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-217 YES YES YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-335-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES YES YES hsa-miR-375 YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-425-5p YES YES YES hsa-miR-448 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-543 YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES YES Display: