ctcRbase

Entry Detail

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General Information

Database ID: SKCM03673 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UBE4A Full Name: ubiquitination factor E4A Category: mRNA Synonyms: E4|UBOX2|UFD2 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 118359585 End Site(bp): 118399211 Gene Summary: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000110344 HGNC ID: HGNC:12499 Entrez Gene: 9354

Expression Profile of UBE4A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1197 YES NO YES hsa-miR-124-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-186-5p YES NO NO hsa-miR-195-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-497-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-613 YES YES YES hsa-miR-653-5p YES YES NO Display: