ctcRbase

Entry Detail

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General Information

Database ID: SKCM03791 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SP3 Full Name: Sp3 transcription factor Category: mRNA Synonyms: SPR2 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 173906459 End Site(bp): 173965702 Gene Summary: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000172845 HGNC ID: HGNC:11208 Entrez Gene: 6670

Expression Profile of SP3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-151a-3p YES NO YES hsa-miR-153-3p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-194-5p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-208a-3p YES YES YES hsa-miR-208b-3p YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-376c-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-421 YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-543 YES NO YES hsa-miR-655-3p YES NO YES hsa-miR-7-5p YES YES NO hsa-miR-96-5p YES YES YES Display: