ctcRbase

Entry Detail

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General Information

Database ID: SKCM03941 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SPRY4 Full Name: sprouty RTK signaling antagonist 4 Category: mRNA Synonyms: HH17 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 142310427 End Site(bp): 142326455 Gene Summary: This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014] External Links: Ensembl ID: ENSG00000187678 HGNC ID: HGNC:15533 Entrez Gene: 81848

Expression Profile of SPRY4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-1321 YES NO NO hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-140-3p YES NO YES hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES NO YES hsa-miR-147a YES NO NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-200a-3p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-21-5p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-300 YES NO YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-381-3p YES NO YES hsa-miR-411-5p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES NO hsa-miR-454-3p YES NO YES hsa-miR-497-5p YES YES YES hsa-miR-519d-3p YES NO YES hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-590-5p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-93-5p YES NO YES Display: