ctcRbase

Entry Detail

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General Information

Database ID: SKCM04789 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PLEKHA1 Full Name: pleckstrin homology domain containing A1 Category: mRNA Synonyms: TAPP1 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 122374696 End Site(bp): 122442602 Gene Summary: This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010] External Links: Ensembl ID: ENSG00000107679 HGNC ID: HGNC:14335 Entrez Gene: 59338

Expression Profile of PLEKHA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1323 YES NO NO hsa-miR-134-5p YES YES NO hsa-miR-1-3p NO YES YES hsa-miR-150-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-185-5p NO YES YES hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-206 NO YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-31-5p NO YES YES hsa-miR-32-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-422a YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-548o-3p YES NO NO hsa-miR-590-5p YES YES YES hsa-miR-613 NO YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES NO YES Display: