ctcRbase

Entry Detail

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General Information

Database ID: SKCM04863 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: IGF1R Full Name: insulin like growth factor 1 receptor Category: mRNA Synonyms: CD221|IGFIR|IGFR|JTK13 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 98648971 End Site(bp): 98964530 Gene Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] External Links: Ensembl ID: ENSG00000140443 HGNC ID: HGNC:5465 Entrez Gene: 3480

Expression Profile of IGF1R Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-100-5p YES NO YES hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-1271-5p YES NO YES hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-139-5p YES NO YES hsa-miR-140-5p YES NO YES hsa-miR-141-3p YES NO YES hsa-miR-143-3p YES NO YES hsa-miR-145-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-153-3p YES NO YES hsa-miR-15a-5p YES NO NO hsa-miR-15b-5p YES NO NO hsa-miR-16-5p YES NO NO hsa-miR-182-5p YES YES YES hsa-miR-185-5p YES NO NO hsa-miR-186-5p YES YES YES hsa-miR-194-5p YES NO YES hsa-miR-195-5p YES NO NO hsa-miR-200a-3p YES NO YES hsa-miR-223-3p YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-376a-3p YES NO YES hsa-miR-376b-3p YES NO YES hsa-miR-378a-3p YES NO YES hsa-miR-379-5p YES NO YES hsa-miR-422a YES NO YES hsa-miR-424-5p YES NO NO hsa-miR-448 YES YES YES hsa-miR-455-5p YES NO YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES NO NO hsa-miR-497-5p YES NO NO hsa-miR-503-5p YES NO NO hsa-miR-505-3p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-663a YES NO NO hsa-miR-7-5p YES NO YES hsa-miR-96-5p YES NO YES hsa-miR-98-5p YES NO YES hsa-miR-99a-5p YES NO YES hsa-miR-99b-5p YES NO YES Display: