ctcRbase

Entry Detail

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General Information

Database ID: SKCM05611 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LMBR1 Full Name: limb development membrane protein 1 Category: mRNA Synonyms: ACHP|C7orf2|DIF14|LSS|PPD2|THYP|TPT|ZRS Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 156668946 End Site(bp): 156893230 Gene Summary: This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000105983 HGNC ID: HGNC:13243 Entrez Gene: 64327

Expression Profile of LMBR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-1-3p YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-192-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES NO YES hsa-miR-215-5p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-217 YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-324-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-613 YES NO YES hsa-miR-708-5p YES YES NO Display: