ctcRbase

Entry Detail

---



General Information

Database ID: SKCM05756 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EED Full Name: embryonic ectoderm development Category: mRNA Synonyms: COGIS|HEED|WAIT1 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 86244544 End Site(bp): 86278813 Gene Summary: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000074266 HGNC ID: HGNC:3188 Entrez Gene: 8726

Expression Profile of EED Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-188-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-323a-3p YES NO YES hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES YES YES hsa-miR-7-5p YES YES YES hsa-miR-873-5p YES YES NO Display: