ctcRbase

Entry Detail

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General Information

Database ID: SKCM05814 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: KAZN Full Name: kazrin, periplakin interacting protein Category: mRNA Synonyms: KAZ Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 13892792 End Site(bp): 15118043 Gene Summary: This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000189337 HGNC ID: HGNC:29173 Entrez Gene: 23254

Expression Profile of KAZN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1297 YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-205-5p YES NO YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-31-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-424-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-625-5p YES NO NO Display: