ctcRbase

Entry Detail

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General Information

Database ID: SKCM05819 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: P4HA2 Full Name: prolyl 4-hydroxylase subunit alpha 2 Category: mRNA Synonyms: MYP25 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 132191838 End Site(bp): 132295315 Gene Summary: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000072682 HGNC ID: HGNC:8547 Entrez Gene: 8974

Expression Profile of P4HA2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-342-3p YES YES YES hsa-miR-361-5p YES YES YES hsa-miR-365a-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-9-5p YES YES YES hsa-miR-98-5p YES NO YES Display: